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. Author manuscript; available in PMC: 2017 Jul 6.
Published in final edited form as: Annu Rev Biophys. 2015;44:311–337. doi: 10.1146/annurev-biophys-051013-023008

Figure 4.

Figure 4

The membrane domain of complex I from T. thermophilus (PDB entry 4HE8). Inverted-topology repeats related by a two-fold (22) screw-axis are colored blue to red for the first repeat or dark gray for the second repeat. The single ‘repeat’ in subunit Nqo8 has same TM topology as the three ‘first repeats’, but is rotated by 180° around an axis perpendicular to the membrane plane (cf. dark blue helices), and is more tilted. Nqo8 is separated from Nqo14 by a number of additional subunits (purple). Other non-symmetric segments and subunits are colored white.