Table 3. Association of cardiometabolic traits and synchrony measures.
Longitudinal segmental synchrony | Transverse segmental synchrony | |||
---|---|---|---|---|
estimate (s.e.) | P | estimate (s.e.) | P | |
Primary traits | ||||
Body mass index | 0.02 (0.005) | 0.003 | 0.01 (0.006) | 0.11 |
Triglycerides | -0.003 (0.005) | 0.59 | -0.003 (0.006) | 0.63 |
HOMA-IR | 0.02 (0.008) | 0.05 | 0.02 (0.009) | 0.05 |
C-reactive protein | 0.0003 (0.005) | 0.96 | -0.006 (0.006) | 0.31 |
Secondary traits | ||||
Waist circumference | 0.03 (0.01) | 0.006 | 0.01 (0.01) | 0.42 |
Fasting glucose | -0.008 (0.006) | 0.20 | -0.01 (0.007) | 0.09 |
HDL cholesterol | -0.007 (0.006) | 0.21 | -0.02 (0.007) | 0.008 |
Diabetes mellitus | 0.08 (0.02) | <0.0001 | 0.05 (0.02) | 0.02 |
Adiponectin | 0.0006 (0.005) | 0.90 | 0.004 (0.006) | 0.54 |
Leptin | 0.01 (0.007) | 0.15 | 0.01 (0.008) | 0.07 |
Leptin receptor | -0.001 (0.004) | 0.76 | -0.006 (0.005) | 0.20 |
Aldosterone/renin ratio | 0.006 (0.004) | 0.14 | -0.007 (0.005) | 0.14 |
Beta estimate represents the change in echo variable (synchrony expressed in ms) per 1-standard deviation change in continuous clinical traits, and for the presence versus absence of dichotomous traits. Multivariable model adjusted for age, sex, body mass index, heart rate, systolic blood pressure, hypertension treatment, diabetes mellitus, HDL cholesterol, triglyceride concentrations. Biomarkers are log-transformed.