Table 4. Comparison of demographic, medication, treatments, and clinical characteristics between those with and without hospital re-encounter after the baseline visit.
| Variable | Rehospitalization encounter after baseline visit | P-value* | ||
|---|---|---|---|---|
| Yes (n = 641) | No (n = 416) | |||
| Demographic Variables | ||||
| Age at baseline visit | 67.8±9.7 | 66.5±9.6 | 0.032 | |
| Diagnosis Variables | ||||
| Motor Fluctuations | No | 278 (43.4%) | 220 (53.1%) | 0.002 |
| Yes | 362 (56.6%) | 194 (46.9%) | ||
| Hoehn and Yahr Stage | 1 | 42 (6.6%) | 56 (13.5%) | <0.0001 |
| 2 | 248 (38.7%) | 180 (43.3%) | ||
| 3 | 229 (35.7%) | 124 (29.8%) | ||
| 4–5 | 76 (11.9%) | 24 (5.8%) | ||
| Not Assessed | 46 (7.2%) | 32 (7.7%) | ||
| Medications | ||||
| Levodopa | No | 36 (5.6%) | 48 (11.6%) | 0.0005 |
| Yes | 603 (94.4%) | 366 (88.4%) | ||
| MAO-B | No | 506 (79.4%) | 303 (73.7%) | 0.031 |
| Yes | 131 (20.6%) | 108 (26.3%) | ||
| COMT | No | 481 (75.6%) | 337 (81.8%) | 0.019 |
| Yes | 155 (24.4%) | 75 (18.2%) | ||
| Amantadine | No | 484 (76.0%) | 339 (82.5%) | 0.012 |
| Yes | 153 (24.0%) | 72 (17.5%) | ||
| Antidepressant | No | 350 (54.9%) | 282 (68.6%) | <0.0001 |
| Yes | 287 (45.1%) | 129 (31.4%) | ||
| Other Treatment (after visit) | ||||
| Speech Therapy | No | 549 (86.5%) | 372 (90.5%) | 0.048 |
| Yes | 86 (13.5%) | 39 (9.5%) | ||
| Deep Brain Stimulation | No change | 567 (91.7%) | 384 (95.3%) | 0.029 |
| Refer for eval | 51 (8.3%) | 19 (4.7%) | ||
| First Year Clinical Condition | ||||
| Disease Duration | 10.4±6.4 | 8.9±6.3 | 0.0004 | |
| Number of Comorbidities | 2.4±1.4 | 2.0±1.3 | < .0001 | |
| Number of Medications | 2.7±1.2 | 2.3±1.2 | < .0001 | |
| PDQ39 Emotion | 7.1±5.1 | 6.2±4.7 | 0.0015 | |
| PDQ39 Total Score | 29.7±16.0 | 25.2±14.7 | < .0001 | |
| MCSI Index | 22.7±16.4 | 18.9±15.0 | 0.003 | |
| Standardized TUG | 0.2±1.0 | 0.0±1.0 | < .0001 | |
*P-values are from two-sample t-test for the continuous variables and a Chi-square test for the categorical variables.