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. Author manuscript; available in PMC: 2018 May 15.
Published in final edited form as: Cancer Res. 2017 Apr 17;77(10):2674–2685. doi: 10.1158/0008-5472.CAN-16-3128

Figure 3. SSRP1 interacts with the N-terminus of XRCC1 independent of XRCC1 phosphorylation or interaction with PARP1.

Figure 3

A. Schematic representation of XRCC1 domains used in this study. B. 293 cells expressing both Flag-tagged XRCC1 deletions and a pEGFP-SSRP1/pEGFP-C1 vector were immunoprecipitated by GFP antibody. Western blot (WB) with anti-Flag and anti-GFP is shown. C. 293 cells expressing GFP-SSRP1 and Flag-tagged XRCC1 deletions were immunoprecipitated using GFP antibody. WB with anti-Flag and anti-GFP is shown. D. 293 cells expressing GFP-tagged WT XRCC1 (left); CKM-XRCC1 and myc-SSRP1 (right) were immunoprecipitated by GFP antibody. WB with anti-SSRP1, anti-Flag and anti-GFP is shown.