Table 4.
Percent variation explained.
MHBMA (ng/mL) N = 1009 |
Overall Percent Variation Explained | Whites | African Americans | Japanese Americans | ||||
---|---|---|---|---|---|---|---|---|
| ||||||||
n | Meana | n | Meana | n | Meana | |||
Sex + Age + BMI + Batch + TNE + CPD | 44.23% | 385 | 5.73 | 304 | 6.15 | 320 | 3.29 | |
p-values | – | 0.27 | <0.0001 | |||||
+ GSTT1_deletion | 7.30% | 385 | 5.30 | 304 | 5.95 | 320 | 3.76 | |
p-values | – | 0.05 | <0.0001 | |||||
+ GSTM1_deletion | 0.88% | 385 | 5.56 | 304 | 5.92 | 320 | 3.91 | |
p-values | – | 0.29 | <0.0001 | |||||
| ||||||||
DHBMA (ng/mL) N = 1009 |
||||||||
|
||||||||
Sex + Age + BMI + Batch + TNE + CPD | 32.12% | 385 | 306.1 | 304 | 352.2 | 320 | 294.7 | |
p-values | – | 0.02 | 0.506 | |||||
+ GSTT1_deletion | 0.16% | 385 | 306.7 | 304 | 350.3 | 320 | 288.3 | |
p-values | – | 0.03 | 0.31 | |||||
+ GSTM1_deletion | 0.00% | 385 | 305.3 | 304 | 349.2 | 320 | 286.8 | |
p-values | – | 0.03 | 0.29 | |||||
| ||||||||
MHBMA / (MHBMA + DHBMA) N = 1009 |
||||||||
|
||||||||
Sex + Age + BMI + Batch + TNE + CPD | 11.05% | 385 | 0.020 | 304 | 0.018 | 320 | 0.012 | |
p-values | – | 0.32 | <0.0001 | |||||
+ GSTT1_deletion | 11.40% | 385 | 0.018 | 304 | 0.018 | 320 | 0.014 | |
p-values | – | 0.77 | <0.0001 | |||||
+ GSTM1_deletion | 1.12% | 385 | 0.019 | 304 | 0.018 | 320 | 0.015 | |
p-values | – | 0.28 | <0.0001 |
All Means are expressed as geometric least squares means adjusted for age, gender, BMI, batch, TNE (CPD, GSTT1, and GSTM1 where appropriate).