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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2017 Mar 14;26(7):1034–1042. doi: 10.1158/1055-9965.EPI-16-0838

Table 4.

Percent variation explained.

MHBMA (ng/mL)
N = 1009
Overall Percent Variation Explained Whites African Americans Japanese Americans

n Meana n Meana n Meana
Sex + Age + BMI + Batch + TNE + CPD 44.23% 385 5.73 304 6.15 320 3.29
p-values 0.27 <0.0001
+ GSTT1_deletion 7.30% 385 5.30 304 5.95 320 3.76
p-values 0.05 <0.0001
+ GSTM1_deletion 0.88% 385 5.56 304 5.92 320 3.91
p-values 0.29 <0.0001

DHBMA (ng/mL)
N = 1009

Sex + Age + BMI + Batch + TNE + CPD 32.12% 385 306.1 304 352.2 320 294.7
p-values 0.02 0.506
+ GSTT1_deletion 0.16% 385 306.7 304 350.3 320 288.3
p-values 0.03 0.31
+ GSTM1_deletion 0.00% 385 305.3 304 349.2 320 286.8
p-values 0.03 0.29

MHBMA / (MHBMA + DHBMA)
N = 1009

Sex + Age + BMI + Batch + TNE + CPD 11.05% 385 0.020 304 0.018 320 0.012
p-values 0.32 <0.0001
+ GSTT1_deletion 11.40% 385 0.018 304 0.018 320 0.014
p-values 0.77 <0.0001
+ GSTM1_deletion 1.12% 385 0.019 304 0.018 320 0.015
p-values 0.28 <0.0001
a

All Means are expressed as geometric least squares means adjusted for age, gender, BMI, batch, TNE (CPD, GSTT1, and GSTM1 where appropriate).