Table 2.
Characteristic | No detected PD-L1(+) CCAMs | >0–1.1 PD-L1(+) CCAMs/mL | >1.1 PD-L1(+) CCAMs/mL | p-value |
---|---|---|---|---|
Lung Cancer Cohort | 86 | 12 | 14 | |
| ||||
Age, median (IQR), years | 67 (60–74) | 68.5 (61.75–75.75) | 70 (59–76.5) | 0.851 |
| ||||
Tumor AJCC Stage | ||||
I | 42 | 7 | 2 | 0.0265 |
II | 12 | 2 | 2 | |
III | 22 | 0 | 4 | |
IV | 10 | 3 | 6 | |
| ||||
Tumor Histological Type | ||||
Adenocarcinoma | 62 | 7 | 11 | 0.918 |
Squamous Cell Carcinoma | 14 | 3 | 2 | |
Other | 10 | 2 | 1 | |
| ||||
Clinical Site | ||||
Yale | 61 | 8 | 3 | 0.00743 |
Billings | 19 | 2 | 8 | |
UCSD | 6 | 2 | 3 | |
| ||||
Unhealthy Controls | 16 | 4 | 0 |
CCAM = Circulating Cells Associated with Malignancy
IQR = Interquartile range
AJCC = American Joint Committee on Cancer