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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Mol Cancer Ther. 2017 Apr 26;16(7):1401–1411. doi: 10.1158/1535-7163.MCT-17-0099

Figure 2. Ref-1 redox controls NF-κB DNA binding in leukemia T-cells.

Figure 2

A) Competitive EMSA for NF-κB using nuclear extracts from TAIL7 cells in the presence of WT or NF-κB-binding-defective cold probe (25-, 50- or 75-fold). B) NF-κB redox-EMSA in extracts from TAIL7 cells treated with increasing doses of E3330. DTT final dose was 0.02mM. C). Densitometry quantification of effect of E3330 on NF-κB DNA binding in TAIL7 cells; data shown as mean ± SEM from two independent experiments. *p<0.05, **p<0.01, using T-test.