Table 5.
Multivariable analysis for the factors contributing to the prevalence of individual symptoms#
| Sensation abnormality† | Pain† | Fatigue† | Cognitive disturbance† | Depression† | Anxiety† | |
|---|---|---|---|---|---|---|
| OR (95% CI) |
OR (95% CI) |
OR (95% CI) |
OR (95% CI) |
OR (95% CI) |
OR (95% CI) |
|
| Cancer experience (Ref: Non-cancer individuals) | ||||||
| Cancer survivors | 1.31* (1.01, 1.70) |
1.47** (1.14, 1.89) |
1.36* (1.05, 1.75) |
1.05 (0.80, 1.39) |
1.05 (0.81, 1.35) |
1.18 (0.94, 1.48) |
| Number of chronic conditions (Ref: none) | ||||||
| 1 | 2.27*** (1.92, 2.69) |
6.58*** (5.30, 8.16) |
3.40*** (2.76, 4.17) |
3.01*** (2.46, 3.69) |
2.38*** (2.00, 2.85) |
2.37*** (2.00, 2.80) |
| 2 and above | 4.49*** (3.35, 6.03) |
27.02*** (16.8, 44.3) |
6.48*** (4.58, 9.16) |
3.66*** (4.98, 8.88) |
3.68*** (2.82, 4.81) |
3.65*** (2.67, 5.00) |
| Age at survey (Ref: 18–44.9 years old) | ||||||
| 45–64.9 years old | 1.73*** (1.47, 2.03) |
1.02 (0.86, 1.20) |
0.68*** (0.58, 0.80) |
1.43*** (1.17, 1.74) |
0.81* (0.67, 0.95) |
0.82* (0.69, 0.98) |
| ≥65 years old | 2.39*** (1.89, 3.01) |
0.78* (0.62, 0.98) |
0.40*** (0.32, 0.49) |
1.67*** (1.29, 2.16) |
0.46 (0.36, 0.58) |
0.45*** (0.36, 0.56) |
| Gender (Ref: Male) | ||||||
| Female | 0.88 (0.77, 1.01) |
1.37*** (1.20, 1.56) |
1.66*** (1.45, 1.90) |
0.98 (0.83, 1.15) |
1.59*** (1.39, 1.82) |
1.55*** (1.36, 1.78) |
| Race/ethnicity (Ref: White) | ||||||
| Hispanic | 0.65*** (0.54, 0.79) |
0.70*** (0.59, 0.84) |
0.59*** (0.49, 0.71) |
0.89 (0.71, 1.12) |
0.62*** (0.51, 0.75) |
0.67*** (0.55, 0.82) |
| Non-Hispanic Black | 0.73** (0.60, 0.88) |
0.83 (0.69, 1.01) |
0.60** (0.56, 0.85) |
0.89 (0.70, 1.14) |
0.72** (0.59, 0.87) |
0.57*** (0.47, 0.69) |
| Non-Hispanic Asian | 0.79 (0.60, 1.04) |
0.54*** (0.41, 0.71) |
0.71* (0.53, 0.94) |
0.96 (0.68, 1.35) |
0.61** (0.45, 0.82) |
0.78 (0.60, 1.02) |
| Non-Hispanic other races | 2.05* (1.00, 4.19) |
1.01 (0.52, 1.97) |
0.68 (0.31, 1.50) |
0.55 (0.17, 1.75) |
0.81 (0.37, 1.78) |
0.48 (0.20, 1.17) |
| Marital status (Ref: Married) | ||||||
| Separated | 1.26 (0.87, 1.82) |
1.48* (1.03, 2.14) |
1.15 (0.77, 1.72) |
1.54* (1.03, 2.30) |
1.67** (1.18, 2.38) |
1.80** (1.25, 2.60) |
| Divorced | 1.10 (0.92, 1.34) |
1.29* (1.06, 1.56) |
1.23 (0.99, 1.53) |
1.10 (0.87, 1.39) |
1.34** (1.11, 1.62) |
1.15 (0.95, 1.39) |
| Single/never married | 0.90 (0.75, 1.07) |
0.91 (0.77, 1.07) |
0.90 (0.76, 1.08) |
1.04 (0.82, 1.32) |
1.17 (0.98, 1.39) |
1.14 (0.97, 1.34) |
| Widowed | 1.27 (0.97, 1.66) |
0.94 (0.71, 1.25) |
0.82 (0.63, 1.05) |
1.25 (0.88, 1.61) |
1.22 (0.96, 1.55) |
0.97 (0.76, 1.24) |
| Education (Ref: Graduate degree) | ||||||
| Below high school | 1.26 (0.98, 1.64) |
1.09 (0.83, 1.44) |
0.90 (0.68, 1.19) |
2.18*** (1.56, 3.04) |
1.16 (0.87, 1.55) |
0.83 (0.64, 1.09) |
| High school/GED | 1.04 (0.84, 1.29) |
1.12 (0.87, 1.43) |
0.91 (0.72, 1.15) |
1.61** (1.19, 2.18) |
1.00 (0.79, 1.28) |
0.86 (0.69, 1.08) |
| Some college | 0.99 (0.79, 1.25) |
1.20 (0.95, 1.53) |
0.92 (0.73, 1.15) |
1.35 (0.89, 1.87) |
0.98 (0.77, 1.25) |
0.96 (0.77, 1.21) |
| Bachelor degree | 0.91 (0.72, 1.14) |
0.90 (0.69, 1.18) |
0.82 (0.63, 1.05) |
1.06 (0.74, 1.51) |
0.94 (0.72, 1.23) |
1.12 (0.87, 1.45) |
#
Numbers were weighted to represent the entire U.S. non-institutionalized adults.
†
Six multivariable models were performed to identify the determinants for the prevalence of individual symptom phenotypes.
*
p<0.05;
**
p<0.01,
***
p<0.001.