Table 3.
PDT dose | [1O2]rx (mM) | In-air Fluence (J/cm2) | ϕair (mW/cm2) | Photofrin (μM) | Mice number |
---|---|---|---|---|---|
1200 μM J/cm2 < PDT dose | 1.3-2-2 | 250 | 75 | 9.9–12.6 | 3 |
| |||||
800<PDT dose≤1200 μM J/cm2 | 0.3–1.3 | 135 | 75 | 7.2–12.1 | 6 |
1.3–1.8 | 250 | 75 | 5.3–7.0 | 2 | |
| |||||
400<PDT dose≤800 μM J/cm2 | 0.6–1.02 | 135 | 75 | 5.5–6.7 | 5 |
0.8 | 200 | 150 | 4.7–4.9 | 2 | |
1.2–1.4 | 250 | 50 | 1.9–4.1 | 2 | |
0.9–1.09 | 250 | 150 | 3.3–6.9 | 5 | |
| |||||
PDT dose≤400 μM J/cm2 | 0.3–0.4 | 50 | 50 | 2.8–4.9 | 4 |
0.4 | 50 | 75 | 4.3–7.5 | 5 | |
0.2–0.3 | 50 | 150 | 2.9–8.8 | 4 | |
0.5–0.9 | 135 | 50 | 2.0–4.3 | 4 | |
0.7 | 135 | 75 | 3.1 | 1 | |
0.5–0.6 | 135 | 150 | 3.0–3.8 | 4 | |
0.3–1.0 | 200 | 50 | 1.0–3.7 | 5 | |
0.6–0.75 | 200 | 150 | 2.7–3.5 | 3 | |
0.6–1.0 | 250 | 50 | 3.9–4.9 | 2 | |
0.6–0.8 | 250 | 75 | 1.9–2.7 | 5 | |
0.3–0.6 | 250 | 150 | 1.0–2.0 | 4 |