Table 4.
The amounts of reacted singlet oxygen concentration calculated for each PDT treatment condition.
[1O2]rx | PDT dose (μM J/cm2) | In-air Fluence (J/cm2) | ϕair (mW/cm2) | Photofrin (μM) | Mice number |
---|---|---|---|---|---|
1.1 mM≤[1O2]rx | 977–1148 | 135 | 75 | 10.1–12.1 | 4 |
418–530 | 250 | 50 | 1.9–4.1 | 2 | |
1555–1998 | 250 | 75 | 5.3–12.6 | 5 | |
| |||||
0.734≤[1O2]rx<1.1mM | 324 | 135 | 50 | 4.3 | 1 |
487–1029 | 135 | 75 | 5.5–7.2 | 5 | |
148–278 | 200 | 50 | 1.6–3.0 | 2 | |
390–579 | 200 | 150 | 3.5–4.9 | 3 | |
354 | 250 | 50 | 4.9 | 1 | |
254–308 | 250 | 75 | 2.4–2.7 | 3 | |
410–611 | 250 | 150 | 3.3–6.9 | 5 | |
| |||||
0.367≤[1O2]rx<0.734mM | 166 | 50 | 50 | 0.4 | 1 |
210–302 | 50 | 75 | 5.3–7.5 | 4 | |
155–239 | 135 | 50 | 2.0–3.0 | 3 | |
256–688 | 135 | 75 | 3.1–6.7 | 2 | |
262–358 | 135 | 150 | 2.9–3.8 | 4 | |
165–346 | 200 | 50 | 1.8–3.7 | 2 | |
276–309 | 200 | 150 | 2.7–2.9 | 2 | |
197 | 250 | 50 | 3.9 | 1 | |
199–332 | 250 | 75 | 1.9–2.1 | 2 | |
174–227 | 250 | 150 | 1.5–2.0 | 3 | |
| |||||
[1O2]rx<0.367mM | 106–122 | 50 | 50 | 2.8–3.2 | 3 |
165 | 50 | 75 | 4.3 | 1 | |
114–366 | 50 | 150 | 2.9–8.8 | 4 | |
974 | 135 | 75 | 9.1 | 1 | |
94 | 200 | 50 | 1.0 | 1 | |
101 | 250 | 150 | 1.0 | 1 |