Table 6.
PDT dose and [1O2]rx threshold for Photofrin, 2-(1-Hexyloxyethyl)-2- devinylpyropheophorbide (HPPH) (30) and benzoporphyrin derivative monoacid ring A (BPD) (31) photosensitizers.
| Photosensitizers | ε† (μM−1cm−1) | λ‡ (nm) | PDT dose threshold (μM J cm−2) | Photosensitizer absorbed dose | [1O2]rx (mM) | Refs. | |
|---|---|---|---|---|---|---|---|
|
| |||||||
| (J/cm3) | (Photons/cm3) | ||||||
| Photofrin | 0.0035 | 630 | 1200 | 4.2 | 13.4×1018 | 1.1 | This study |
| HPPH | 0.108 | 665 | 52.62 | 5.7 | 19 ×1018 | 1.2 | (30) |
| BPD | 0.078 | 690 | 52.94 | 4.1 | 14.3 ×1018 | 1.15 | (31) |
†
Extinction coefficient of the photosensitizer
‡
Wavelength of the excitation light