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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Calcif Tissue Int. 2017 Apr 3;101(2):193–203. doi: 10.1007/s00223-017-0270-7

Figure 1.

Figure 1

(a) Representative two-dimensional X-ray images demonstrating the skeletal sites used to characterize cortical porosity in the diaphysis of the femur and tibia. In the femur, the sites were at 35, 50, and 75% of the total length, while in the tibia the sites were at 25, 50, and 75% of the total length. (b) Cortical porosity at all 6 skeletal sites at the end of the induction phase (means and standard deviations). The data demonstrate the dramatic increase in cortical porosity induced by the lactation/low Ca model, but no significant increase in the virgin/low Ca model compared to virgin/normal Ca. There were significant between-group differences at all sites investigated with the exception of the distal tibia (p<0.001, p=0.041, and p=0.031, for the distal, midshaft, and distal femur and p=0.010, p=0.013, and p=0.194, for the proximal, midshaft, and distal tibia, respectively). Bars represent significant between-group differences (p<0.05 for the post-hoc tests).