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. 2017 Jun 29;12:4663–4678. doi: 10.2147/IJN.S136646

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© 2017 Tong. This work is published and licensed by Dove Medical Press Limited

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Urine protein/24 h. Urine protein/24 h in rats of the sham, DN, exenatide, and exenatide–PEG-b-(PELG₅₀-g-PLL₃) complex groups were collected after eight weeks, and results were expressed as mean ± SD. A significant increase from the sham group, a significant decrease from the DN (Exenatide-PEG-b-(PELG₅₀-g-PLL₃)) group, and a significant decrease from the DN groups is denoted by *P<0.01, **P<0.01, and ***P<0.01, respectively.

Abbreviations: DN, diabetic nephropathy; PEG-b-(PELG₅₀-g-PLL₃), poly(ethylene glycol)-b-brush poly(L-lysine) polymer.