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. 2017 Jul 6;7:4793. doi: 10.1038/s41598-017-04116-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The expression of HNF-1β was negatively correlated with the prognosis of patients with HCC. (A) HNF-1β immunohistochemical staining patterns in HCC tissues. According to the HNF-1β expression level, HCC patients were divided into an HNF-1β low expression group (the top row) and high expression group (the bottom row). (scale bar = 100 μm). (B) Kaplan-Meier analysis of HNF-1β expression in HCC patients. Low expression of HNF-1β in HCC tissues was associated with prolonged disease-free survival. The P value calculated by the log-rank test is indicated (P = 0.001).