Table 1.

Univariate and multivariate analysis of DFS in HCC patients.

Variable	Number	Univariate analysis	Multivariate
		P value	HR (95% CI)	P value
Tumour HNF-1B expression
Low vs High	57 vs 33	0.001*	2.406 (1.415,4.092)	0.007*
Tumour size
<5 cm vs ≥ 5 cm	38 vs 52	0.010*		NS
Tumour number
Single vs Multiple	92 vs 8	0.339		NA
Cirrhosis
No vs Yes	24 vs 66	0.001*		NS
TNM stage
I/II vs III	82 vs 8	0.005*	3.596 (1.388,9.314)	0.008*
HbsAg
Negative vs Positive	74 vs 16	0.794		NA
Serum AFP
<400 vs ≥400	67 vs 23	0.499		NA
Edmondson grade
I/II vs III	62 vs 28	0.021*	1.776 (1.086,2.907)	0.022*
Encapsulation
No vs Yes	26 vs 64	0.142		NA
Portal vein thrombosis
No vs Yes	65 vs 25	0.147		NA
Microvascular invasion
No vs Yes	35 vs 55	0.451		NA
Macrovascular invasion
No vs Yes	85 vs 5	0.005*		NS

NA, not adopted; NS, not significant; HR, hazard ratio; Factors with p < 0.05 in univariate analysis were used for further multivariate analysis. *P < 0.05 was considered statistically significant.