Table 1.
The shared motifs by GSs in each cancer type.
| Cancer type | Shared motifs, their SIOMICS P-values | Most similar known motifs, TFs and the corresponding STAMP E-values | ||
|---|---|---|---|---|
| Breast cancer | GGGSTGGG | 3.88e-11 | RGGSTGGG | CAC-binding protein (3.92e-11) |
| GGGAGRGG | 1.71e-12 | GGGAGGG | MAZ (1.52e-09) | |
| GGGCKGGG | 2.46e-12 | GGGCGGGGN | SP1 (1.42e-11) | |
| GGCRGGGC | 4.97e-10 | NNGGGCGGGGCNN | GC (5.60e-10) | |
| CCCGGCSC | 5.66e-09 | NTGCACNCGGCCC | MTF1 (MTF-1) (8.63e-07) | |
| TGGGGCTG | 7.74e-10 | TNGGGGTN | KLF6 (GBF) (3.21e-08) | |
| GCMGCCGCC | 9.65e-08 | GCCGCC | BRF2 (ERF2) (1.57e-08) | |
| Colorectal cancer | GGGSTGGG | 1.96e-13 | RGGSTGGG | CAC-binding protein (2.93e-11) |
| CCAGCCCC | 4.39e-10 | CCCKCCCCN | SP1 (7.92e-08) | |
| GCCCCAGGCC | 2.43e-09 | NNNCCNCNGGCN | TFAP2A (AP-2) (4.47e-08) | |
| GGGGSTGG | 2.99e-12 | TNGGGGTN | KLF6 (GBF) (3.15e-08) | |
| GCCCCAGC | 7.05e-08 | CCGCCCNCNNC | EGR1 (KROX) (3.38e-06) | |
| Leukemia | GGGAGRGG | 2.48e-12 | GGGAGGG | MAZ (1.84e-10) |
| GGGCKGGG | 2.55e-08 | GGGCGGGGN | SP1 (4.83e-12) | |
| Lymphoma | NGGGCGGGS | 4.66e-12 | NGGGGCGGGGNN | SP1 (3.83e-13) |
| TGGGMGGG | 4.54e-20 | GGGAGGG | MAZ (3.93e-10) | |
| GGCKGGGC | 4.48e-08 | NNGGGCGGGGCNN | GC (7.99e-09) | |
| CKGGCTGGGG | 4.39e-34 | RGGSTGGG | CAC-binding protein (1.80e-06) | |
| Lung cancer | CCCCTYCC | 8.29e-21 | NCCCCCCNCCC | ZNF219 (1.48e-08) |
| GGKGKGRG | 8.16e-09 | SGGGGGGGGMNN | PATZ1 (MAZR) (4.07e-07) | |
| CCCGCSCC | 4.25e-09 | CCCKCCCCN | SP1 (3.43e-10) | |
| GGGTTGGGAG | 8.91e-10 | TTGGGAGR | IKZF1 (Lyf-1) (4.75e-08) | |
| AGGGCTGGGS | 2.20e-12 | RGGSTGGG | CAC-binding (1.51e-07) | |
IUPAC code is used in the motif consensus: S (G or C), R (A or G), M (A or C), K (G or T), Y (C or T), N (any base).