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. 2017 Jun 28;11:1957–1967. doi: 10.2147/DDDT.S129447

Figure 1.

Figure 1

Outline of a PDD pipeline.

Notes: A PDD design pipeline consisting of collected information from various diseases and disorders, selecting small-molecule library and in vitro or in vivo models to perform unbiased screening followed by analysis and quantification of the phenotype. The identified hits are then tested on preclinical and disease animal models before moving toward clinical trials and applications.

Abbreviation: PDD, phenotype-based drug discovery.