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. 2017 Jul 6;7:4772. doi: 10.1038/s41598-017-05118-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Population comparison of the relative effectiveness of normal housing versus cross-modal exposure in instantiating multisensory integration capabilities. (A) A high proportion of neurons exhibit multisensory enhancement capabilities in normal animals. (B) However, few SC neurons in noise-reared animals exhibited this capacity. (C) This proportion increased somewhat, but not significantly, when those animals were subsequently housed in a normal environment for 6 months (NE-6). (D1) This proportion also failed to change significantly in animals remaining in that housing condition for an additional 6 months (NE-12). (D2) However, the animals given once weekly cross-modal exposure sessions over an equivalent period did achieve a normal incidence of neurons with this capacity (VA trained). E and F) Group differences were evident in the summary bar graphs which compare the incidences of multisensory enhancement (E), and the mean ME magnitudes (F) collapsed over the last 1.5 months of testing. n = number of neurons.