Table 2.
SNPs that may be associated with the differential expression of CYP2D6 in breast cancer cells.
| SNP Id | Genomic location | Calculated diff. expression | Alt. allele freq. in AA | Alt. allele freq. in CA | Alt. allele freq. in AS | Effect size in eQTL | Distance to TSS |
|---|---|---|---|---|---|---|---|
| rs7245 | 22:42481849 | 0.2279 | 0.97 | 0.54 | 0.61 | 0.53 | 355 kb |
| rs5751220 | 22:42516205 | 0.2236 | 0.97 | 0.54 | 0.62 | 0.52 | 390 kb |
| rs6002626 | 22:42517989 | 0.2279 | 0.97 | 0.54 | 0.61 | 0.53 | 391 kb |
| rs714002 | 22: 42569024 | 0.2548 | 0.7 | 0.21 | 0.28 | 0.52 | 442 kb |
| rs713811 | 22:42569870 | 0.2496 | 0.69 | 0.21 | 0.27 | 0.52 | 443 kb |
| rs2011944 | 22:42569999 | 0.2444 | 0.68 | 0.21 | 0.27 | 0.52 | 443 kb |