Figure 7.

Morphological changes in pancreatic islets. The tissue sections were stained with murine monoclonal antibodies to insulin with diaminobenzidine as chromogenic substrate, additional staining was performed with hematoxylin. Intact (IN)—intact group of healthy animals; the prevalence of insulin-positive β-endocrine cells. Control (C)—saline-treated group with experimental type 2 diabetes mellitus; the decrease in insulin-positive material. ZB—group of animals treated with ZB-16; the moderate increase in β-endocrine cells in comparison to the saline-treated group.