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. 2017 Jul 7;8:783. doi: 10.3389/fimmu.2017.00783

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Copyright © 2017 Le Page, Garneau, Dupuis, Frost, Larbi, Witkowski, Pawelec and Fülöp.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Determination of the percentage of regulatory T cells (Tregs) in peripheral blood mononuclear cell of healthy, amnestic mild cognitive impairment (aMCI), and mild AD (mAD) subjects. (A) Tregs percentages defined by the CD4⁺FoxP3⁺ markers in individual participants. (B) Corresponding histograms. (C) Tregs percentages defined by the CD4⁺Foxp3⁺CD25^high markers in individual participant. (D) Corresponding histograms. (E) T regs percentages defined by CD4⁺Foxp3⁺CD25⁻ markers in individual participants. (F) Corresponding histograms. Each group was composed of at least five independent subjects with determinations made in triplicate. Data are shown as the mean ± SEM. The asterisks (*) correspond to p < 0.05.