FIGURE 1.

Methodological sketch. Alzheimer’s disease progression is addressed across three stages. Four groups of 36 subjects each at different stages of AD (Control, Early and Late MCI, Alzheimer) following the ADNI classification criterion. All groups have been balanced with respect to age, sex and years of education. Brain connectivity patterns and its relation with disease progression are accomplished by comparing the control group with the rest of groups, i.e., Control vs. EMCI (stage I), Control vs. LMCI (stage II), and Control vs. AD (stage III).