Table 3.

p-values associated to each module from the brain hierarchical atlas.

Module	Control vs. EMCI	Control vs. LMCI	Control vs. AD
1	0.956	0.753	0.023∗
2	0.956	0.466	0.049∗
3	0.956	0.441	0.049∗
4	0.880	0.532	0.031∗
5	0.859	0.689	0.973
6	0.859	0.438	0.546
7	0.956	0.900	0.503
8	0.859	0.449	0.031∗
9	0.859	0.600	0.591
10	0.956	0.900	0.627
11	0.956	0.438	0.759
12	0.956	0.466	0.031∗
13	0.859	0.600	0.531
14	0.956	0.438	0.006∗∗
15	0.956	0.753	0.031∗
16	0.956	0.986	0.031∗
17	0.890	0.898	0.546
18	0.399	0.007∗∗	0.002∗∗∗
19	0.956	0.438	0.109
20	0.956	0.986	0.972

EMCI, Early mild cognitive impairment; LMCI, Late mild cognitive impairment; AD, Alzheimer disease; ^∗0.01 < p < 0.05; ^∗∗0.005 < p < 0.01: ^∗∗∗p < 0.005. Connectivity alterations start in module 18 (marked in black and underlined), and in later stages grow (increasing significance) and extend to a multitude of different other modules.