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. 2017 Jul 7;8:450. doi: 10.3389/fphar.2017.00450

FIGURE 1.

FIGURE 1

Experimental design and time-line. (A) Male and female rats were exposed to intermittent ethanol exposure during either adolescence (blue) or adulthood (red). All rats underwent five cycles of exposure to ethanol. For adolescent ethanol exposed rats, exposure occurred between PND 28–44 and testing occurred after PND 80. For adult exposed rats, exposure occurred between PND 70–86 and testing occurred after PND 120. (B) Each cycle of ethanol exposure consisted of two 14-h exposures that began 3 h prior to the start of the light cycle and ended 1 h prior to the start of the dark cycle.