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. 2017 May 30;40(4):543–554. doi: 10.1007/s10545-017-0052-4

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — HSC-GT for MLD restores ARSA activity in granulocytes and CSF. (a) ARSA activity measured on peripheral blood CD15⁺ granulocytes. The green box represents the normal activity range collected from six healthy volunteers; (b) ARSA activity measured on CSF of patients at 6, 12, 24 and 36 months follow up. The green horizontal line represents the mean data collected from the activity range measured from three healthy donors (Sessa et al 2016)