Table 1. Comparison of demographics and clinical characteristics between COPD and ACO.
| Characteristics | COPD (n=1,281) | ACO (n=223) | P value |
|---|---|---|---|
| Demographics | |||
| Female | 121 (9.5) | 10 (4.5) | 0.015 |
| Age | 71.6±7.7 | 71.0±7.7 | 0.285 |
| Pack-year | 44.0±25.5 | 45.1±24.9 | 0.584 |
| Current smoker | 323 (25.3) | 73 (32.9) | 0.026 |
| BMI | 22.7±3.4 | 23.2±3.3 | 0.058 |
| Symptoms | |||
| Cough | 308 (24.3) | 55 (24.9) | 0.859 |
| Sputum | 403 (32.0) | 80 (36.4) | 0.198 |
| CAT | 15.9±7.9 | 15.1±7.8 | 0.172 |
| SGRQ | 35.3±19.1 | 31.0±18.0 | 0.002 |
| Lung function | |||
| FEV1% | 55.1±17.9 | 52.7±14.5 | 0.051 |
| FVC% | 80.6±17.5 | 81.1±17.6 | 0.693 |
| FEV1/FVC | 48.2±12.1 | 46.6±9.5 | 0.055 |
| Comorbidity | |||
| HTN | 496 (39.1) | 72 (32.7) | 0.074 |
| DM | 213 (16.8) | 28 (12.7) | 0.131 |
| MI | 66 (5.3) | 7 (3.2) | 0.191 |
| HF | 46 (3.7) | 6 (2.7) | 0.497 |
| Hyperlipidemia | 135 (10.8) | 16 (7.3) | 0.118 |
| Allergic rhinitis | 131 (10.4) | 25 (11.4) | 0.662 |
| Atopic dermatitis | 39 (3.1) | 5 (2.3) | 0.518 |
Data are shown as mean ± standard deviation or number (%).
COPD, chronic obstructive pulmonary disease; ACO, asthma-chronic obstructive pulmonary disease overlap; BMI, body mass index; CAT, chronic obstructive pulmonary disease assessment test; SGRQ, St. George Respiratory Questionnaire; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; HTN, hypertension; DM, diabetes mellitus; MI, myocardial infarction; HF, heart failure.