Table 1.
XWnt8-mFzd8 CRD complex | Mouse modelsa | Human modelsa | |
---|---|---|---|
MolProbity score | 1.72 | 2.13 ± 0.46 | 2.08 ± 0.42 |
TM-scoreb | 1.00 | 0.91 ± 0.04 | 0.91 ± 0.05 |
Cα RMSD (Å)b | 0.00 | 1.39 ± 0.39 | 1.39 ± 0.45 |
a Mean values ±2 S.D. shown; data for individual complexes shown in supplemental Tables S5–S10.
b TM-score and Cα RMSD values calculated with respect to the XWnt8-mFzd8 CRD complex (Protein Data Bank code 4F0A). By definition, the TM-score for an optimally overlaid structure compared with itself is 1; the RMSD for an optimally overlaid structure compared with itself is 0.