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Progressive ectopic mineralization of MGP-deficient nasal septum. Histological analysis of Mgp−/− nasal septa by VKVG staining of 7-μm-thick plastic sections showing the initiation of pathologic cartilage mineralization at 1 week of age and its progression until 5 weeks of age (n = 3 mice for each time point). The last panel represents an unmineralized WT nasal septum at 5 weeks of age stained with VKVG. Scale bar = 40 μm.
