Figure 6.

MGP-deficient mice have a shorter nasal septum. A, exposed cartilaginous nasal septa of 5-week-old WT and Mgp^−/− mice stained with Safranin O. Measurement of the lengths presented as relative length ratio shows a significantly smaller nasal septum in Mgp^−/− mice. B, 2D cephalometric analysis of the viscerocranium and basicranium of 5-week-old WT and Mgp^−/− mice. The viscerocranium (1–2) in Mgp^−/− mice is significantly smaller compared with WT mice, whereas the total basicranial length (2–5) is not affected. Values represent the ratio of the linear distance between points over the total cranial length (1–5). A description of the anatomical locations of the landmarks is presented in supplemental Table S2 (n = 5 in both groups). Statistical analysis: Student's t test in all cases.