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. 2017 Feb 13;36(26):3661–3672. doi: 10.1038/onc.2016.519

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Copyright © 2017 The Author(s)

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In cancer tissue from GIST patients, Kit(mut) accumulates on the Golgi apparatus. (a–f) Paraffin-embedded tumor tissue specimens were immuno-stained with anti-Kit (a, b, d and e; blue), anti-PDGFRα (c and f; blue), anti-GM130 (Golgi matrix protein 130 kDa; green), and Höechst33342 (DNA; white). Bars, 20 μm. (g) The graph shows Pearson’s R correlation coefficients (Pearson’s R) between GM130 vs Kit or PDGFRα. Results are means±s.d. (n=3–13). ***P<0.001.