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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: J Clin Psychiatry. 2017 Jun;78(6):e656–e667. doi: 10.4088/JCP.16r11113

Figure 2. S-adenosylmethionine in the Methylation Cycle.

Figure 2

DHF, dihydrofolate; THF, tetrahydrofolate; 5-MTHF, 5-methyltetrahydrofolate; SAMe, S-adenosylmethionine; SAH, S-adenosylhomocysteine; MTHFR, methylenetetrahydrofolate reductase; MTR, methionine synthase; MAT, methionine adenosyltransferase; SAHH, S-adenosylhomocysteine hydrolase.

Reproduced with permission from Psychiatric Clinics of North America17