Figure 4.

Typical flux measurements under different osmotic conditions in the presence and absence of the inhibitory peptide. The flux was determined indirectly by measuring the mass difference of the insert over time. While normally the cells can cope with a rather high osmotic gradient for water into the lumen, the inhibitory peptide impairs this ability. Under isotonic conditions the peptide has no visible effect. The panels correspond to 3 independent measurements on different trans well filters.