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. 2017 May 10;130(1):48–58. doi: 10.1182/blood-2016-04-711820

Table 1.

Percentage of D835 mutations in ITD+ and native FLT3 (ITD) alleles in complementary DNA from patients who relapse on quizartinib

Patient number Sequences ITD+/– Mutation No. of ITD+/– sequences sampled Observed alternative codon frequency of ITD+ or ITD alleles (%)
1005-006 ITD+ D835Y 261 39.50
ITD+ D835F 261 2.70
ITD D835Y 564 16.80
1005-007 ITD+ D835V 378 47.40
ITD+ D835Y 378 4.00
ITD D835V 255 24.70
1005-009 ITD+ D835Y 445 50.60
ITD D835Y 10 50.00
1009-003 ITD+ D835F 322 10.60
ITD+ D835Y 322 8.70
ITD+ D835V 322 3.40
ITD D835Y 266 7.50
ITD D835F 266 3.80
1009-007 ITD+ D835Y 235 55.70
ITD D835Y 393 25.20
1011-006 ITD+ D835Y 402 41.00
ITD D835Y 825 9.20
1011-007 ITD+ D835V 436 29.60
ITD+ D835Y 436 3.00
ITD D835V 64 28.10