Table 4.
Pathway | P value | Overlap | Target molecules in data set |
---|---|---|---|
Insulin receptor signaling | 2.25E-03 | 3.5% (5/141) | CBL, SOS1, GSK3B, EIF2B2, PRKAG1 |
Prostate cancer signaling | 3.26E-03 | 4.3% (4/94) | TFDP1, SOS1, GSK3B, BCL2 |
Melanocyte development and pigmentation signaling | 3.38E-03 | 4.2% (4/95) | SOS1, RPS6KA3, PRKAG1, BCL2 |
Mitochondrial L-carnitine shuttle pathway | 5.30E-03 | 11.8% (2/17) | ACSL3, CPT1A |
PTEN signaling | 7.50E-03 | 3.4% (4/119) | CBL, SOS1, GSK3B, BCL2 |