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. 2017 Apr 7;12(6):433–440. doi: 10.1080/15592294.2017.1303581

Table 4.

Ingenuity Pathway Analysis canonical pathways.

Pathway P value Overlap Target molecules in data set
Insulin receptor signaling 2.25E-03 3.5% (5/141) CBL, SOS1, GSK3B, EIF2B2, PRKAG1
Prostate cancer signaling 3.26E-03 4.3% (4/94) TFDP1, SOS1, GSK3B, BCL2
Melanocyte development and pigmentation signaling 3.38E-03 4.2% (4/95) SOS1, RPS6KA3, PRKAG1, BCL2
Mitochondrial L-carnitine shuttle pathway 5.30E-03 11.8% (2/17) ACSL3, CPT1A
PTEN signaling 7.50E-03 3.4% (4/119) CBL, SOS1, GSK3B, BCL2