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Red solid circles represent a freshly prepared formulation while blue solid circles represent a clinical formulation stored at 2-8°C for: (A) 3 months, (B) 9 months, (C) 15 months, (D) 21 months, (E) 27 months, (F) 35 months, (G) 40 months, (H) 46 months, and (I) 52 months. Each bar represents the average and standard deviation of 10 mice at each dose group.
