Table 4.
Short-term (30-day) surgical outcome after one-stage and two-stage management
| One-stage N = 97 | One-stage N = 97 | Two-stage N = 120 | p- value total one-stage vs two-stage | ||
|---|---|---|---|---|---|
| TC approach N = 64 | TD approach N = 33 | Total | |||
| Successful CBD stone clearance, n (%) | |||||
| LC + LCBDE /Index ERCP a | 59 (92.2) | 27(81.8) | 86 (88.7) | 102 (85.0) | 0.66 |
| After conversion to open surgery | 3(4.7) | 5 (15.2) | 8 (8.2) | 16 (13.3) | 0.36 |
| After ERCP for residual stones | 2 (3.1) | 1 (3.0) | 3 (3.1) | 2 (1.7) | 0.15 |
| Total operative time, median (IQR) min b | 140 (69.3) | 165 (52.5) | 150 (61.0) | 112 (64.0) | <0.001 |
| 30-d mortality, n (%) c | 0 (0) | 1 (3.0) | 1 (1.0) | 0 (0) | 0.27 |
| 30-d overall morbidity, n(%) d | 6 (9.4) | 9 (27.2) | 15 (15.5) | 9 (7.5) | 0.64 |
| Surgical morbidity, n (%) | 5(7.8) | 4 (12.1) | 9 (9.3) | 5 (4.2) | 0.13 |
| Bile leak | 2 | 3 | 5 | 0 | |
| Postoperative bleeding | 1 | 0 | 1 | 2 | |
| Wound infection | 1 | 0 | 1 | 1 | |
| Intra-abdominal abscess | 0 | 1 | 1 | 0 | |
| Post-ERCP pancreatitis | 1 | 0 | 1 | 0 | |
| Bleeding after ERCP | 0 | 0 | 0 | 2 | |
| General morbidity, n (%) | 1 (1.6) | 5 (15.2) | 6 (6.2) | 5 (4.2) | 0.50 |
| Renal insufficiency | 0 | 1 | 1 | 0 | |
| Fever, unknown origin | 0 | 0 | 0 | 1 | |
| Vocal cord injury from intubation | 0 | 1 | 1 | 0 | |
| Myocardial infarction | 0 | 0 | 0 | 1 | |
| Heart insufficiency | 1 | 0 | 1 | 1 | |
| Pneumonia | 0 | 3 | 3 | 2 | |
| Dindo-Clavien gr IIIb-V, n (%) | 2 (3.1) | 3 (9.1) | 5 (5.2) | 2 (1.7) | 0.25 |
| Postoperative stay, median (IQR) days b | 2 (1–3) | 5 (2–8) | 2 (2–5) | 4.5 (3–7) | <0.001 |
| Reoperation, n (%) | 2 (3.1) | 2 (6.1) | 4 (4.1) | 1 (0.8) | 0.11 |
| Readmission, n(%) | 3 (4.7) | 16 (48.5) | 19 (19.6) | 7 (5.8) | 0.002 |
TC transcystic, TD transductal
aTwo-stage group
bTwo-stage: ERCP and LC time
cClostridium perfringens sepsis
dFigures in the columns are not additive because some patients had more than one complication