Skip to main content
. Author manuscript; available in PMC: 2018 Jun 23.
Published in final edited form as: Neuroscience. 2017 May 3;354:136–145. doi: 10.1016/j.neuroscience.2017.04.036

Figure 7. IGF1 acutely induces tactile allodynia in HFD mice without affecting blood glucose levels.

Figure 7

(A) Tactile responses to von Frey filaments for HFD mice receiving saline (HFD saline), insulin at 2U (HFD 2U insulin) or IGF1 at 2mg/kg (HFD 2mg/kg IGF1). Two-way repeated measures ANOVA followed by Tukey’s post hoc test, *p<0.05, ***p<0.001 vs baseline, n=8. (B) Blood glucose levels in HFD mice receiving saline (HFD saline), insulin at 2U (HFD 2U insulin) or IGF1 at 2mg/kg (HFD 2mg/kg IGF1). Two-way repeated measures ANOVA followed by Tukey’s post hoc test, **p<0.01, ***p<0.001 vs baseline, n=8. Mean+s.e.m.