Table 6.
Cox proportional hazards model of time to lung cancer incidence according to amount of current total physical activity (MET-min/wk) by BMI, smoking categories, and age groups
| Total physical activity MET-min/wk | BMI
|
|||||
|---|---|---|---|---|---|---|
| <25 kg/m2
|
25 to <30 kg/m2
|
≥30 kg/m2
|
||||
| No. of cases | HR* (95% CI) | No. of cases | HR* (95% CI) | No. of cases | HR* (95% CI) | |
| 0 to <100 | 206 | Ref. | 192 | Ref. | 183 | Ref. |
|
| ||||||
| 100 to <500 | 203 | 0.68 (0.56–0.83) | 207 | 0.86(0.71–1.05) | 178 | 1.08 (0.88–1.33) |
|
| ||||||
| 500 to <1,200 | 228 | 0.69 (0.57–0.84) | 194 | 0.82 (0.67–1.00) | 113 | 1.00 (0.79–1.26) |
|
| ||||||
| 1,200+ | 237 | 0.81 (0.67–0.98) | 129 | 0.77 (0.61–0.96) | 78 | 1.25 (0.95–1.63) |
|
| ||||||
| p Values for interaction between physical activity and BMI 0.01. | ||||||
| Total physical activity MET-min/wk | Smoking categories
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Never smoker
|
Former smoker, <10 pack years
|
Former smoker, ≥10 pack years
|
Current smoker
|
|||||
| No. of cases | HR* (95% CI) | No. of cases | HR* (95% CI) | No. of cases | HR (95% CI) | No. of cases | HR* (95% CI) | |
| 0 to <100 | 80 | Ref. | 24 | Ref. | 233 | Ref. | 244 | Ref. |
|
| ||||||||
| 100 to <500 | 104 | 0.93 (0.69–1.25) | 41 | 1.14 (0.69–1.89) | 248 | 0.83 (0.69–0.99) | 195 | 0.79 (0.65–0.95) |
|
| ||||||||
| 500 to <1,200 | 84 | 0.76 (0.56–1.04) | 50 | 1.20 (0.74–1.96) | 278 | 0.82 (0.69–0.98) | 123 | 0.70 (0.57–0.88) |
|
| ||||||||
| 1,200+ | 79 | 0.97 (0.71–1.32) | 51 | 1.44 (0.88–2.34) | 237 | 0.85 (0.70–1.02) | 77 | 0.70 (0.54–0.90) |
|
| ||||||||
| p Values for interaction between physical activity and smoking 0.39. | ||||||||
| Total physical activity MET-min/wk | Age groups
|
|||||
|---|---|---|---|---|---|---|
| <50 to 59
|
60–69
|
70 to 79+
|
||||
| No. of cases | HR* (95% CI) | No. of cases | HR* (95% CI) | No. of cases | HR* (95% CI) | |
| 0 to <100 | 137 | Ref. | 295 | Ref. | 149 | Ref. |
|
| ||||||
| 100 to <500 | 115 | 0.82 (0.64–1.05) | 310 | 0.87 (0.74–1.02) | 163 | 0.86 (0.69–1.08) |
|
| ||||||
| 500 to <1,200 | 94 | 0.76 (0.58–0.99) | 294 | 0.87 (0.73–1.02) | 147 | 0.79 (0.63–1.00) |
|
| ||||||
| 1,200+ | 70 | 0.73 (0.55–0.98) | 247 | 0.96 (0.81–1.15) | 127 | 0.91 (0.71–1.16) |
|
| ||||||
| p Values for interaction between physical activity and age 0.80. | ||||||