Table 9.
Cox proportional hazards model of time to lung cancer mortality according to amount of current (study entry) total physical activity (MET-min/wk) by lung cancer subtype
MET minutes per week | No. of cases | Unadjusted model
|
Adjusted model*
|
||
---|---|---|---|---|---|
HR (95% CI) | Global p values | HR (95% CI) | Global p values | ||
NSCLC subtype | |||||
| |||||
0 to <100 | 269 | Ref. | 0.0001 | Ref. | 0.02 |
| |||||
100 to <500 | 256 | 0.92 (0.77–1.09) | 0.98 (0.82–1.16) | ||
| |||||
500 to <1,200 | 217 | 0.72 (0.60–0.86) | 0.80 (0.66–0.98) | ||
| |||||
1,200+ | 179 | 0.70 (0.58–0.85) | 0.76 (0.62–0.94) | ||
| |||||
SCLC subtype | |||||
| |||||
0 to <100 | 51 | Ref. | 0.55 | Ref. | 0.46 |
| |||||
100 to <500 | 38 | 0.93 (0.61–1.42) | 1.10 (0.61–1.99) | ||
| |||||
500 to <1,200 | 31 | 0.73 (0.47–1.15) | 0.68 (0.38–1.25) | ||
| |||||
1,200+ | 32 | 0.99 (0.63–1.54) | 0.99 (0.56–1.76) | ||
| |||||
NSCLC-squamous | |||||
| |||||
0 to <100 | 44 | Ref. | 0.15 | Ref. | 0.07 |
| |||||
100 to <500 | 44 | 1.02 (0.67–1.55) | 0.96 (0.56–1.64) | ||
| |||||
500 to <1,200 | 26 | 0.61 (0.37–0.99) | 0.57 (0.31–1.03) | ||
| |||||
1,200+ | 22 | 0.81 (0.49–1.36) | 0.52 (0.26–1.04) | ||
| |||||
NSCLC-adenocarcinoma | |||||
| |||||
0 to <100 | 126 | Ref. | 0.0008 | Ref. | 0.02 |
| |||||
100 to <500 | 108 | 0.75 (0.58–0.97) | 0.81 (0.62–1.07) | ||
| |||||
500 to <1,200 | 115 | 0.66 (0.52–0.86) | 0.72 (0.54–0.96) | ||
| |||||
1,200+ | 99 | 0.60 (0.46–0.79) | 0.64 (0.48–0.87) | ||
| |||||
NSCLC-other | |||||
| |||||
0 to <100 | 101 | Ref. | 0.42 | Ref. | 0.23 |
| |||||
100 to <500 | 105 | 1.22 (0.92–1.60) | 1.37 (1.01–1.85) | ||
| |||||
500 to <1,200 | 78 | 0.98 (0.72–1.32) | 1.15 (0.80–1.64) | ||
| |||||
1,200+ | 60 | 1.10 (0.80–1.52) | 1.13 (0.78–1.66) |