Table 7. Cox proportional hazards model for RAS.

Using BAL CXCR3 ligand concentration principal component cutoffs.

	Univariable		Multivariable ƚ
	HR (95% CI)	p-value	HR (95% CI)	p-value
OP	2.41 (1.37–4.25)	0.002	1.91 (1.05–3.45)	0.033
OP with PC > 25th%	2.38 (1.19–4.75)	0.014	1.86 (0.90–3.83)	0.092
OP with PC > 50th%	2.82 (1.41–5.64)	0.003	2.16 (1.05–4.46)	0.037
OP with PC > 75th%	4.06 (1.97–8.37)	0.001	3.03 (1.39–6.60)	0.005

Definition of abbreviations: CLAD = chronic lung allograft dysfunction; HR = hazards ratio; CI = confidience interval; OP = organizing pneumonia; PC = First principal component; % = percentile.

^ƚ Multivariable model adjusted for diffuse alveolar damage, acute rejection, and lymphocytic bronchiolitis. Double lung transplant recipients only.