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. 2017 Jul 7;12(7):e0180037. doi: 10.1371/journal.pone.0180037

Table 2. Plasma pharmacokinetic parameters of PTX after intravenous administration of Taxol and DEX-IND/PTX micelles in rats (n = 5).

Parameters Formulations
Taxol DEX-IND/PTX
AUC0-∞/ng·mL-1·h-1 99.71 ± 19.347 300.069 ± 89.089
MRT0-∞/h 7.936 ± 1.06 13.234 ±11.175
CL/L·h-1·kg-1 0.103 ± 0.019 0.036 ± 0.011

AUC, area under the concentration-time curve; MRT, mean residence time; CL, clearance rate.