Table 1. Characteristics of patients with pulmonary hypertension (PH).
| Variables | All patients (n = 41) |
PAH (n = 12) |
CTEPH (n = 29) |
P-value of PAH vs. CTEPH |
|---|---|---|---|---|
| Gender, no. (%) | 0.276 | |||
| Male | 13 (31.7%) | 2 (16.7%) | 11 (37.9%) | |
| Female | 28 (68.3%) | 10 (83.3%) | 18 (62.1%) | |
| Age, years | 57.3 ± 2.8 | 41.2 ± 5.1 | 63.7 ± 2.6 | < 0.001* |
| Mean PAP, mmHg | 43.9 ± 1.5 | 51.0 ± 2.9 | 40.9 ± 1.5 | 0.002* |
| Mean RAP, mmHg | 6.1 ± 0.6 | 6.3 ± 1.0 | 6.0 ± 0.7 | 0.800 |
| PCWP, mmHg | 8.1 ± 0.4 | 8.0 ± 0.7 | 8.1 ±0.5 | 0.906 |
| PVR, Wood units | 11.2 ± 1.1 | 16.2 ± 2.7 | 9.2 ± 0.8 | 0.002* |
| Cardiac output, L/min | 3.7 ± 0.2 | 3.3 ± 0.4 | 3.9 ± 0.2 | 0.171 |
| Cardiac index, L/min/m2 | 2.4 ± 0.1 | 2.2 ± 0.3 | 2.5 ± 0.1 | 0.175 |
| BNP, pg/mL | 191 ± 35 | 204 ± 82 | 186 ± 36 | 0.816 |
| 6MWD, m | 369 ± 19 | 383 ± 28 | 363 ± 25 | 0.651 |
| Serum 25(OH)D levels, ng/mL | 18.5 ± 1.0 | 13.1 ± 1.5 | 20.7 ± 1.0 | < 0.001* |
Abbreviations: PAH, idiopathic or heritable pulmonary arterial hypertension; CTEPH, chronic thromboembolic pulmonary hypertension; PAP, pulmonary arterial pressure; RAP, right atrial pressure; PCWP, pulmonary capillary wedge pressure; PVR, pulmonary vascular resistance; BNP, B-type natriuretic peptide; 6MWD, six-minute-walk distance; 25(OH)D, 25-hydroxyvitamin D. Data are mean ± SEM.
*P < 0.01.