Figure 1.

Genistein inhibits retinoblastoma cell viability and growth and induces apoptosis. Y79 cells were treated with 50 μM genistein or dimethyl sulfoxide (DMSO). A: A Cell Counting Kit-8 assay was used to determine cell viability. B: Cloning efficiency was measured by the number of clones growing in soft agar. C: Cell apoptosis was analyzed with flow cytometry as described. Data were presented as mean ± standard deviation (SD) from three independent experiments with triple replicates per experiment. **p<0.01 indicates a statistically significant difference compared with the DMSO group.