Figure 4.
Effects of stress and social defeat in 0.36 mm diameter punch samples of CeA and BLA. Control females (n=9) had significantly more Dnmt1 expression in the CeA compared to control males (n=12, A). Dnmt1 expression was reduced in stressed females (n=7) compared to control females. There was no difference in Dnmt1 expression between stressed males (n=7) and control males. No differences in Dnmt1 were observed in BLA (C). No differences in Bdnf were observed in CeA (B) or BLA (D). * p < 0.05 vs. control male. † p < 0.05 vs. control female. (CeA = central amygdala, BLA = basolateral amygdala, Dnmt1 = DNA methyltransferase 1, Bdnf = brain-derived neurotrophic growth factor)