. Author manuscript; available in PMC: 2017 Jul 7.

Published in final edited form as: Res Comput Mol Biol. 2017 Apr 12;10229:336–352. doi: 10.1007/978-3-319-56970-3_21

Table 2.

Single base-pair mutation overlapping a binding site for TF Creb1. The wild-type and mutated binding sites are shown in bold. The mutated position is underlined. (The 6-mers in parentheses are the reverse complements of 6-mers in the original sequence. In these cases the reverse complement 6-mers were used as features because they are alphabetically ranked lower that the corresponding 6-mers on the forward strand.)

Wild-Type	Mutant
CCCATTGACGTCAATGGG	CCCATTGCCGTCAATGGG
CATTGA	CATTGC
ATTGAC	ATTGCC
TTGACG (CGTCAA)	TTGCCG (CGGCAA)
TGACGT (ACGTCA)	TGCCGT (ACGGCA)
GACGTC	GCCGTC (GACGGC)
ACGTCA	CCGTCA