Table 3.
Comparison between 6-mer OLS models and PWM models for four TFs with MPRA data available from [15]. The numbers represent areas under the receiver-operating characteristic (ROC) curve, for false positive rates between 0 and 0.2. The maximum value for the area under the curve is 0.2. The expected value for random models is 0.02. Results show that 6-mer OLS models outperform PWM models for 3 out of the 4 TFs tested.
| Hnf1 | Hnf4 | Gata | Foxa | |
|---|---|---|---|---|
| PWM models | 0.04556 | 0.02082 | 0.07014 | 0.04835 |
| 6-mer OLS models | 0.06667 | 0.04868 | 0.05046 | 0.05275 |