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Proposed bacteriocin resistance mechanism mediated by TCSs in S. mutans. BceRS is related to bacitracin resistance by regulating BceAB ABC transporter. NsrRS is related to nisin A resistance by regulatiing NsrX which has ability to bind nisin A, suggesting trap nisin A. LcrRS is related to nukacin ISK-I and lacticin 481 resistance by regulating LctFEG ABC transporter.
