Table 5.
Bidirectionally released proteins found among proteins enriched within a three-fold of Syntenin-1 in apical and basolateral exosome preparations from polarized RPE monolayers.
| Protein name | Gene name | Enrichment ranking* | |
|---|---|---|---|
| Apical | Basolateral | ||
| Syntenin-1 | SDCBP | 4 | 13 |
| CD81 | CD81 | 1 | 21 |
| Hsp70-interacting protein | ST13 | 5 | 28 |
| ALIX | PDCD6IP | 17 | 16 |
| Heat shock 70 kDa protein 1B | HSPA1B | 12 | 22 |
| Annexin A1 | ANXA1 | 35 | 20 |
| Annexin A2 | ANXA2 | 46 | 11 |
| A Disintegrin And Metalloproteinase Domain 10 | ADAM10 | 48 | 18 |
| Heat Shock Protein Family A (Hsp70) Member 2 | HSPA2 | 26 | 43 |
| EGF Like Repeats and Discoidin Domains 3 | EDIL3 | 42 | 38 |
| 5′-Nucleotidase Ecto | NT5E | 44 | 41 |
| Solute Carrier Family 2 Member 1 (GLUT1) | SLC2A1 | 55 | 37 |
Proteins are shown in order of the average of enrichment in apical and basolateral exosome preparations.
*Enrichment ranking in the pure exosome preparation by descending pure-to-crude ratio of the relative abundance of each protein.