Table 4.
Variable | All patients | Low risk of PPCs | Increased risk of PPCs | Relative Risk (95% CI) | P |
Any de-saturation | 3.9 (387/9844) | 3.3 (219/6736) | 5.6 (150/2658) | 1.78 (1.44 to 2.20) | <0.001 |
Unplanned recruitment manoeuvre | 3.4 (332/9837) | 2.5 (171/6731) | 5.6 (148/2657) | 2.26 (1.81 to 2.83) | <0.001 |
Ventilatory pressure reduction | 2.9 (282/9830) | 2.2 (147/6730) | 4.6 (122/1651) | 2.16 (1.69 to 2.76) | <0.001 |
Expiratory flow limitation | 0.5 (52/9786) | 0.4 (25/6703) | 0.9 (24/2635) | 2.45 (1.40 to 4.31) | 0.001 |
Hypotension | 26.6 (2617/9845) | 23.7 (1594/6737) | 35.3 (939/2659) | 1.76 (1.60 to 1.94) | <0.001 |
Vasoactive drugs | 22.4 (2208/9845) | 18.5 (1246/6737) | 33.7 (897/2659) | 2.24 (2.03 to 2.48) | <0.001 |
New arrhythmias | 0.6 (60/9838) | 0.4 (24/6732) | 1.2 (32/2657) | 3.41 (2.00 to 5.79) | <0.001 |
Low versus increased risk of PPCs, according to the Assess Respiratory Risk in Surgical Patients in Catalonia risk (ARISCAT) score (<26 versus ≥26, respectively).
Data are presented as % (n/N). Comparison of differences within a subgroup is performed by using the t-test for continuous variables and χ2 for categorical variables.
CI, confidence interval; n, number with characteristic; PPC, postoperative pulmonary complication; N, number in group or subgroup.
Definitions of intraoperative events: Any de-saturation, defined as the occurrence of SpO2 <92%; unplanned recruitment manoeuvre, ventilation strategies aimed at restoring lung aeration; ventilation pressure reduction, ventilation strategies aimed at lowering peak and/or plateau pressures; expiratory flow limitation, defined as expiratory flow higher than zero at end-expiration as suggested by visual analysis of the expiratory gas flow curve; hypotension, defined as systolic arterial pressure <90 mmHg for 3 min or longer; need for vasoactive drugs, defined as any vasoactive drug given to correct hypotension; new-onset arrhythmias, defined as new onset of atrial fibrillation, sustained ventricular tachycardia, supraventricular tachycardia, or ventricular fibrillation.