Table 1.
The SNPs identified in A. baumannii during infection.
| Gene | Gene_product | Freq | Amino acid alteration | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| ptk | Tyrosine-protein kinase, autophosphorylates | 9 | S550L | G667D | H118R | L528F | A531V | L669F | T650A | R483H | I75N |
| TE32_03770 | Type I secretion C-terminal target domain-containing protein | 8 | T22T | T62R | A36A | I50I | I6I | A52D | A17T | I74I | |
| TE32_03765 | Putative cell-surface adhesin | 4 | P728P | T720T | V712V | T728T | |||||
| TE32_02230 | Outer membrane protein A precursor (190 kDa antigen) | 3 | V469V | L446L | G308G | ||||||
| tadA | Deaminase | 3 | Y126C | S37P | P37S | ||||||
| bauA | Outer membrane receptor | 3 | A391T | A391T | A391V | ||||||
| adeS | Two-component sensor | 3 | N127K | Y31N | R161C | ||||||
| Hypothetical protein_1 | Hypothetical protein | 2 | Q104H | L66I | |||||||
| TE32_07715 | Transposase (integrase catalytic subunit) | 2 | E244D | I223N | |||||||
| tufB | Elongation factor Tu | 2 | Y201Y | E381E | |||||||
| tnpA | IS6 family transposase | 2 | N184D | G184D | |||||||
| ampC | Beta-lactamase | 2 | G247S | V236A | |||||||
| HMPREF0010_03281 | Glycosyltransferase | 2 | F225S | L341S | |||||||
| ygeV | Transcriptional regulator | 2 | R284H | A140T | |||||||
| Hypothetical protein_2 | Hypothetical protein | 2 | I146I | G56E | |||||||
Genes identified as being independently mutated in two or more of the lineages.